| Date | Location | Result | |
| Dec 03, 2010 | Minneapolis, MN | Creighton 3, Iowa State 2 (27-25,16-25,25-23,19-25,15-11) | Box score |
| Nov 24, 2010 | Lubbock, Texas | Iowa State 3, Texas Tech 1 (25-19,25-14,25-27,25-14) | Box score |
| Nov 21, 2010 | College Station, TX | Iowa State 3, Texas A&M 1 (25-23,16-25,25-17,25-23) | Box score |
| Nov 13, 2010 | Norman, OK | Oklahoma 3, Iowa State 1 (24-26,25-21,25-20,25-23) | Box score |
| Oct 30, 2010 | Lincoln, Nebraska | Nebraska 3, Iowa State 0 (25-19,25-16,25-16) | Box score |
| 11-27-2010 | Ames, Iowa | Texas 3, Iowa State 1 (22-25,25-23,27-25,25-19) | Box score |
| 11-16-10 | Ames, Iowa | Iowa State 3, Colorado 0 (25-13,25-9,25-22) | Box score |
| 11-6-2010 | Ames, Iowa | Missouri 3, Iowa State 1 (19-25,26-24,25-22,26-24) | Box score |
| 11-03-2010 | Ames, Iowa | Iowa State 3, Baylor 0 (25-22,25-22,25-14) | Box score |
| Oct 27, 2010 | Manhattan, Kan. | Iowa State 3, Kansas State 0 (25-14,30-28,25-15) | Box score |
| Oct 23, 2010 | Ames, Iowa | Iowa State 3, Kansas 0 (25-20,25-23,25-20) | Box score |
| Oct 20, 2010 | Boulder, Colo. | Iowa State 3, Colorado 1 (22-25,25-17,25-22,25-10) | Box score |
| Oct 16, 2010 | Ames, Iowa | Iowa State 3, Texas A&M 1 (25-22,21-25,25-11,26-24) | Box score |
| 10-13-2010 | Ames, Iowa | Iowa State 3, Kansas State 0 (25-20,25-22,25-16) | Box score |
| Oct 09, 2010 | Lawrence, Kan. | Kansas 3, Iowa State 1 (25-14,25-23,20-25,25-17) | Box score |
| 10-6-2010 | Ames, Iowa | Iowa State 3, Texas Tech 0 (25-16,25-16,25-18) | Box score |
| 9-29-2010 | Austin, Texas | Texas 3, Iowa State 2 (17-25,25-16,12-25,25-15,15-11) | Box score |
| 9-25-2010 | Ames, Iowa | Iowa State 3, Oklahoma 0 (25-13,25-19,25-23) | Box score |
| 9-22-2010 | Waco, Texas | Iowa State 3, Baylor 1 (21-25,25-20,25-22,25-19) | Box score |
| 9-18-2010 | Columbia, Mo. | Iowa State 3, Missouri 1 (16-25,25-15,25-18,25-19) | Box score |
| 9-15-2010 | Ames, Iowa | Nebraska 3, Iowa State 1 (25-22,24-26,25-23,28-26) | Box score |
| 9-10-2010 | Iowa City, Iowa | Iowa State 3, Iowa 0 (25-15,25-12,25-14) | Box score |
| 9-8-2010 | Ames, Iowa | Iowa State 3, Northern Iowa 0 (25-16,25-20,25-22) | Box score |
| 9-4-2010 | Ames, Iowa | Iowa State 3, FIU 0 (25-12,25-14,25-20) | Box score |
| 9-4-2010 | Ames, Iowa | Iowa State 3, South Dakota State 0 (25-17,26-24,25-22) | Box score |
| 9-3-2010 | Ames, Iowa | Iowa State 3, North Dakota State 1 (25-11,21-25,25-14,25-17) | Box score |
| 9-3-2010 | Ames, Iowa | Iowa State 3, UW-Milwaukee 0 (25-15,25-14,25-18) | Box score |
| 8-29-2010 | Omaha, Neb. | Iowa State 3, Kentucky 1 (25-17,22-25,25-22,25-22) | Box score |
| 8-28-2010 | Omaha, Neb. | Florida 3, Iowa State 1 (25-22,25-21,10-25,25-20) | Box score |